Review of evidence and clinical practice on short versus long fasting times
DOI:
https://doi.org/10.26871/ceus.v6i3.225Keywords:
fasting, diet, fasting preoperativeAbstract
Introduction: preoperative fasting is a period of time in which no food can be ingested in order to minimize perioperative risks. Objective: the aim of this study was to gather evidence on fasting times in order to define an optimal fasting schedule, as well as to know which adjuvants can improve the patient's results and stay. Methods: we conducted a literature review on preoperative fasting, applying search strategies. Results: 59 articles were identified from which 47 were selected that met the assigned inclusion and exclusion criteria. Many clinical practice guidelines recommend less prolonged fasts than the traditional ones. Within the perioperative period, the moment of greatest risk for bronchial aspiration is the anesthetic induction, the main risk factors for bronchial aspiration being a full stomach, abdominal pain, diabetes, trauma related to hypomotility and intestinal obstructions. Conclusions: a preoperative fasting period of 6 hours for solids is recommended for both adults and children, 2 hours of liquids for adults and 1 hour for children. In infants it is advisable to administer breast milk for up to 4 hours and formula milk for up to 6 hours. In addition, the administration of a carbohydrate drink 2 hours before anesthetic induction.
Downloads
References
Mendelson CL. The Aspiration of Stomach Contents into the Lungs During Obstetric Anesthesia. Am J Obstet Gynecol [Internet]. agosto de 1946;52(2):191-205. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0002937816398295
Joshi GP, Abdelmalak BB, Weigel WA, Harbell MW, Kuo CI, Soriano SG, et al. 2023 American Society of Anesthesiologists Practice Guidelines for Preoperative Fasting: Carbohydrate-containing Clear Liquids with or without Protein, Chewing Gum, and Pediatric Fasting Duration—A Modular Update of the 2017 American Society of Anesthesio. Anesthesiology [Internet]. 1 de febrero de 2023;138(2):132-51. Disponible en: https://pubs.asahq.org/anesthesiology/article/138/2/132/137508/2023-American-Society-of-Anesthesiologists
Weimann A, Braga M, Carli F, Higashiguchi T, Hübner M, Klek S, et al. ESPEN practical guideline: Clinical nutrition in surgery. Clin Nutr [Internet]. julio de 2021;40(7):4745-61. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0261561421001783
Dagher C, Tohme J, Bou Chebl R, Chalhoub V, Richa F, Abou Zeid H, et al. Preoperative fasting: Assessment of the practices of Lebanese Anesthesiologists. Saudi J Anaesth [Internet]. 2019;13(3):184. Disponible en: https://journals.lww.com/10.4103/sja.SJA_720_18
Degeeter T, Demey B, Van Caelenberg E, De Baerdemaeker L, Coppens M. Prospective audit on fasting status of elective ambulatory surgery patients, correlated to gastric ultrasound. Acta Chir Belg [Internet]. 2 de enero de 2023;123(1):43-8. Disponible en: https://www.tandfonline.com/doi/full/10.1080/00015458.2021.1940438
Nabi B, Haddadi S, Farzi F, Tehran S, Biazar G, Chaibakhsh Y, et al. Actual Preoperative Fasting Time; A Report From Guilan Academic Hospitals: A Cross-sectional Study. Crescent J Med Biol Sci [Internet]. 9 de septiembre de 2022;10(3):116-20. Disponible en: http://www.cjmb.org/text.php?id=568
Beck-Schimmer B, Bonvini JM. Bronchoaspiration: incidence, consequences and management. Eur J Anaesthesiol [Internet]. febrero de 2011;28(2):78-84. Disponible en: http://journals.lww.com/00003643-201102000-00003
Warner MA, Warner ME, Weber JG. Clinical Significance of Pulmonary Aspiration during the Perioperative Period. Anesthesiology [Internet]. 1 de enero de 1993;78(1):56-62. Disponible en: https://pubs.asahq.org/anesthesiology/article/78/1/56/32911/Clinical-Significance-of-Pulmonary-Aspiration
Kozlow JH, Berenholtz SM, Garrett E, Dorman T, Pronovost PJ. Epidemiology and impact of aspiration pneumonia in patients undergoing surgery in Maryland, 1999–2000. Crit Care Med [Internet]. julio de 2003;31(7):1930-7. Disponible en: http://journals.lww.com/00003246-200307000-00006
Kluger MT, Short TG. Aspiration during anaesthesia: a review of 133 cases from the Australian Anaesthetic Incident Monitoring Study (AIMS). Anaesthesia [Internet]. enero de 1999;54(1):19-26. Disponible en: http://doi.wiley.com/10.1046/j.1365-2044.1999.00642.x
Doctor J, Chandan P, Shetty N, Gala K, Ranganathan P. Ultrasound-guided assessment of gastric residual volume in patients receiving three types of clear fluids: A randomised blinded study. Indian J Anaesth [Internet]. 2021;65(4):289. Disponible en: https://journals.lww.com/ijaweb/Fulltext/2021/04000/Ultrasound_guided_assessment_of_gastric_residual.3.aspx
Gridneva Z, Kugananthan S, Hepworth A, Tie W, Lai C, Ward L, et al. Effect of Human Milk Appetite Hormones, Macronutrients, and Infant Characteristics on Gastric Emptying and Breastfeeding Patterns of Term Fully Breastfed Infants. Nutrients [Internet]. 28 de diciembre de 2016;9(1):15. Disponible en: http://www.mdpi.com/2072-6643/9/1/15
Perrella SL, Hepworth AR, Gridneva Z, Simmer KN, Hartmann PE, Geddes DT. Gastric emptying of different meal volumes of identical composition in preterm infants: a time series analysis. Pediatr Res [Internet]. 20 de abril de 2018;83(4):778-83. Disponible en: https://www.nature.com/articles/pr2017292
Perrella SL, Hepworth AR, Simmer KN, Geddes DT. Influences of Breast Milk Composition on Gastric Emptying in Preterm Infants. J Pediatr Gastroenterol Nutr [Internet]. febrero de 2015;60(2):264-71. Disponible en: https://journals.lww.com/00005176-201502000-00025
Du T, Hill L, Ding L, Towbin AJ, DeJonckheere M, Bennett P, et al. Gastric emptying for liquids of different compositions in children. Br J Anaesth [Internet]. noviembre de 2017;119(5):948-55. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0007091217539082
Lorenzo P, Moreno A, Leza J, Lizasoain I, Moro M, Portolés A. Velázquez. Farmacología Básica y Clínica. 19a ed. Médica Panamericana; 2018. 223-224 p.
Frykholm P, Schindler E, Sümpelmann R, Walker R, Weiss M. Preoperative fasting in children: review of existing guidelines and recent developments. Br J Anaesth [Internet]. marzo de 2018;120(3):469-74. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0007091217540751
Bang YJ, Lee JH, Kim CS, Lee YY, Min JJ. Anxiolytic effects of chewing gum during preoperative fasting and patient-centered outcome in female patients undergoing elective gynecologic surgery: randomized controlled study. Sci Rep [Internet]. 9 de marzo de 2022;12(1):4165. Disponible en: https://www.nature.com/articles/s41598-022-07942-6
Akbuğa GA, Başer M. Effect of preoperative oral liquid carbohydrate intake on blood glucose, fasting-thirst, and fatigue levels: a randomized controlled study. Brazilian J Anesthesiol (English Ed [Internet]. abril de 2021; Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0104001421001329
Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures. Anesthesiology [Internet]. 1 de marzo de 2017;126(3):376-93. Disponible en: https://pubs.asahq.org/anesthesiology/article/126/3/376/19733/Practice-Guidelines-for-Preoperative-Fasting-and
Frykholm P, Disma N, Andersson H, Beck C, Bouvet L, Cercueil E, et al. Pre-operative fasting in children. Eur J Anaesthesiol [Internet]. enero de 2022;39(1):4-25. Disponible en: https://journals.lww.com/10.1097/EJA.0000000000001599
Smith I, Kranke P, Murat I, Smith A, OʼSullivan G, Sreide E, et al. Perioperative fasting in adults and children. Eur J Anaesthesiol [Internet]. agosto de 2011;28(8):556-69. Disponible en: http://journals.lww.com/00003643-201108000-00004
Marquini GV, Pinheiro FE da S, Vieira AU da C, Pinto RM da C, Uyeda MGBK, Girão MJBC, et al. Preoperative Fasting Abbreviation and its Effects on Postoperative Nausea and Vomiting Incidence in Gynecological Surgery Patients. Rev Bras Ginecol e Obs / RBGO Gynecol Obstet [Internet]. 19 de agosto de 2020;42(08):468-75. Disponible en: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1712994
Zhang Y, Min J. Preoperative Carbohydrate Loading in Gynecological Patients Undergoing Combined Spinal and Epidural Anesthesia. J Investig Surg [Internet]. 8 de agosto de 2020;33(7):587-95. Disponible en: https://www.tandfonline.com/doi/full/10.1080/08941939.2018.1546352
Morrison CE, Ritchie-McLean S, Jha A, Mythen M. Two hours too long: time to review fasting guidelines for clear fluids. Br J Anaesth [Internet]. abril de 2020;124(4):363-6. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0007091219310049
Kaye A, Jones M, Viswanath O, Candido K, Boswell M, Soin A, et al. ASIPP Guidelines for Sedation and Fasting Status of Patients Undergoing Interventional Pain Management Procedures. Pain Physician [Internet]. 2019;22(3):201–207. Disponible en: https://www.painphysicianjournal.com/current/pdf?article=NjMwMQ%3D%3D&journal=120
Gamble J, Rosen D. 2023 Canadian Pediatric Anesthesia Society Statement on fasting for elective pediatric anesthesia. Can J Anesth Can d’anesthésie [Internet]. 21 de agosto de 2023;70(8):1295-9. Disponible en: https://link.springer.com/10.1007/s12630-023-02509-z
Thomas M, Morrison C, Newton R, Schindler E. Consensus statement on clear fluids fasting for elective pediatric general anesthesia. Pediatr Anesth [Internet]. 27 de mayo de 2018;28(5):411-4. Disponible en: https://onlinelibrary.wiley.com/doi/10.1111/pan.13370
Hewson DW, Moppett I. Preoperative fasting and prevention of pulmonary aspiration in adults: research feast, quality improvement famine. Br J Anaesth [Internet]. abril de 2020;124(4):361-3. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0007091219309997
Fawcett WJ, Thomas M. Pre‐operative fasting in adults and children: clinical practice and guidelines. Anaesthesia [Internet]. 30 de enero de 2019;74(1):83-8. Disponible en: https://associationofanaesthetists-publications.onlinelibrary.wiley.com/doi/10.1111/anae.14500
Zhang E, Hauser N, Sommerfield A, Sommerfield D, von Ungern‐Sternberg BS. A review of pediatric fasting guidelines and strategies to help children manage preoperative fasting. Pediatr Anesth [Internet]. 2 de agosto de 2023; Disponible en: https://onlinelibrary.wiley.com/doi/10.1111/pan.14738
Yurashevich M, Chow A, Kowalczyk JJ, Traynor AJ, Carvalho B. Preoperative Fasting Times for Patients Undergoing Caesarean Delivery: Before and After a Patient Educational Initiative. Turkish J Anaesthesiol Reanim [Internet]. 17 de julio de 2019;47(4):282-6. Disponible en: http://cms.galenos.com.tr/Uploads/Article_59496/TJAR-47-282-En.pdf
de Klerk ES, de Grunt MN, Hollmann MW, Preckel B, Hermanides J, van Stijn MFM. Incidence of excessive preoperative fasting: a prospective observational study. Br J Anaesth [Internet]. abril de 2023;130(4):e440-2. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0007091222007425
Alsharkh W, Aljuaid M, Huda A, Bawazir A, Alharbi A, Alharbi N. Effect of total fasting hours on the overall quality of recovery after surgery: An observational study. Saudi J Anaesth [Internet]. 2023;17(3):373. Disponible en: https://journals.lww.com/10.4103/sja.sja_71_23
Gul A, Andsoy II, Ozkaya B. Preoperative Fasting and Patients’ Discomfort. Indian J Surg [Internet]. 3 de diciembre de 2018;80(6):549-53. Disponible en: http://link.springer.com/10.1007/s12262-017-1657-4
Halpern SE, Au S, Kesseli SJ, Krischak MK, Olaso DG, Bottiger BA, et al. Lung transplantation using allografts with more than 8 hours of ischemic time: A single-institution experience. J Hear Lung Transplant [Internet]. noviembre de 2021;40(11):1463-71. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S1053249821023226
Silveira SQ, da Silva LM, de Campos Vieira Abib A, de Moura DTH, de Moura EGH, Santos LB, et al. Relationship between perioperative semaglutide use and residual gastric content: A retrospective analysis of patients undergoing elective upper endoscopy. J Clin Anesth [Internet]. agosto de 2023;87:111091. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0952818023000417
Soffin EM, Gibbons MM, Wick EC, Kates SL, Cannesson M, Scott MJ, et al. Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery: Focus on Anesthesiology for Hip Fracture Surgery. Anesth Analg [Internet]. junio de 2019;128(6):1107-17. Disponible en: https://journals.lww.com/00000539-201906000-00013
Witt L, Lehmann B, Sümpelmann R, Dennhardt N, Beck CE. Quality-improvement project to reduce actual fasting times for fluids and solids before induction of anaesthesia. BMC Anesthesiol [Internet]. 26 de diciembre de 2021;21(1):254. Disponible en: https://bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-021-01468-6
Li Y, Su D, Sun Y, Hu Z, Wei Z, Jia J. Influence of different preoperative fasting times on women and neonates in cesarean section: a retrospective analysis. BMC Pregnancy Childbirth [Internet]. 29 de diciembre de 2019;19(1):104. Disponible en: https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-019-2254-2
Panjiar P, Kochhar A, Vajifdar H, Bhat K. A prospective survey on knowledge, attitude and current practices of pre-operative fasting amongst anaesthesiologists: A nationwide survey. Indian J Anaesth [Internet]. 2019;63(5):350. Disponible en: https://journals.lww.com/10.4103/ija.IJA_50_19
Hajian P, Shabani M, Khanlarzadeh E, Nikooseresht M. The Impact of Preoperative Fasting Duration on Blood Glucose and Hemodynamics in Children. J Diabetes Res [Internet]. 21 de agosto de 2020;2020:1-6. Disponible en: https://www.hindawi.com/journals/jdr/2020/6725152/
Tsukamoto M, Hitosugi T, Yokoyama T. Influence of Fasting Duration on Body Fluid and Hemodynamics. Anesth Prog [Internet]. 1 de diciembre de 2017;64(4):226-9. Disponible en: https://meridian.allenpress.com/anesthesia-progress/article/64/4/226/21449/Influence-of-Fasting-Duration-on-Body-Fluid-and
Williams DGA, Molinger J, Wischmeyer PE. The malnourished surgery patient. Curr Opin Anaesthesiol [Internet]. junio de 2019;32(3):405-11. Disponible en: https://journals.lww.com/00001503-201906000-00023
Carvalho CAL de B, Carvalho AA de, Preza ADG, Nogueira PLB, Mendes KBV, Dock-Nascimento DB, et al. Benefícios Metabólicos e Inflamatórios da Abreviação do Jejum Pré-operatório em Cirurgia Pediátrica. Rev Col Bras Cir [Internet]. 2020;47. Disponible en: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912020000100153&tlng=pt
Bang YJ, Lee JH, Kim CS, Choi DC, Noh JJ, Lee YY, et al. The effect of adding chewing gum to oral carbohydrates on preoperative anxiety scores in women undergoing gynecological surgery: A randomized controlled study. Savvas I, editor. PLoS One [Internet]. 25 de abril de 2023;18(4):e0283780. Disponible en: https://dx.plos.org/10.1371/journal.pone.0283780
Bang YJ, Lee EK, Kang R, Kim AH, Kim CS, Sim WS, et al. Effect of chewing gum on anxiety in women undergoing elective cesarean section: a randomized controlled study. Ann Palliat Med [Internet]. mayo de 2023;12(3):529-37. Disponible en: https://apm.amegroups.com/article/view/111589/html
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 JOE KELLER SÁNCHEZ-SALGADO

This work is licensed under a Creative Commons Attribution 4.0 International License.