Keywords
SARS-CoV
Obesity
How to Cite
Abstract
Background: obesity in people with SARS-CoV-2 represents one of the most severe conditions that has caused high peaks in mortality worldwide, due to its consequences associated with obesity. Objective: to relate obesity with SARS-CoV-2 virus infection. Method: this is a systematic review. The search for articles was from January 2020 to May 2021, in the databases: Pubmed, Science Direct and Web of Science, through search terms of the DeCS and MesH, also using Boolean operators AND, OR and NOT. Twenty-one articles met the inclusion criteria. Results: the classification of body weight by BMI was essential to determine that in obese patients (≥30 kg / m2) the incidence percentage was significant in the infection by SARS-CoV-2, being above 20%, developing complications, such as increased hospital stay, admission to the ICU, need for oxygenation, mechanical ventilation and intubation and, in other cases, considerable levels of mortality. Conclusion: obesity turns out to be a risk factor that will complicate the picture in people infected by SARS-CoV-2, through pro-inflammatory mechanisms altering the innate and adaptive immune response leading to a higher risk of infection, little effectiveness of the treatment with antivirals.
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Copyright (c) 2021 Gustavo Mauricio Sánchez-Salazar, Pablo Isaías Urgiles-Siguencia , Michelle Guadalupe Pesantez-Barbecho, Roxana Estefanía Pastuizaca-Paucar