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Abstract
Lipoidoproteinosis (LP) is a rare genodermatosis, of autosomal recessive inheritance, characterized by the deposit of a PAS-positive eosinophilic hyaline material, resistant diastase at the level of the skin, mucosa and internal organs; of which there are approximately 300 - 500 cases published in the literature. Although its prognosis is generally benign and a correlation between increased cancer incidence and LP has not been reported; the expression of extracellular matrix protein-1 (ECM1) has been associated with aspects of malignancy, the genetic alteration that causes LP is found precisely in the gene that encodes this protein. A case of cervical cancer is presented in a patient with this rare condition
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