Keywords
genes
etiology
virulence factors
stomach neoplasms
How to Cite
Abstract
Helicobacter pylori is a Gram-negative bacillus that colonizes the stomach and intestine of approximately half the world's population, although its prevalence varies depending on health conditions, being more frequent in developing countries. Tissue colonization and pathological manifestations of infection depend on the interaction between bacterial virulence factors, host conditions and a number of environmental factors. It is these virulence factors that allow H. pylori to colonize and infect the gastric mucosa, causing inflammatory processes and damage to epithelial cells. In this review, we present updated information on factors related to colonization, adherence and pathogenesis by H. pylori.
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